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- Salmon DNA Injection 婴儿针
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Salmon DNA Injection 婴儿针
*This treatment is performed by Singapore Medical Council (SMC) registered doctors.

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Procedure Type
Injection
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Results
Rejuvenated, healthy and youthful skin
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Downtime
Multiple small bumps over treated area
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Where
Face and neck
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Procedure Time
45 minutes
What Is Salmon DNA Injection?
The salmon DNA injection is a non-invasive cosmetic procedure designed to support your skin’s natural regenerative capabilities. This treatment’s primary ingredient is polynucleotide which is processed from salmon sperm DNA. Polynucleotide stimulates fibroblasts, the cells responsible for collagen production and skin health. The targeted effect is improved skin texture, reduced signs of ageing like hyperpigmentation and wrinkles, and an overall more youthful appearance. It’s not surprising that it eventually earned the moniker of “baby skin injection”, an informal term used by some doctors around the world.
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First, the clinic assistant cleanses your face before applying anaesthetic cream to minimise discomfort. Then, the doctor carefully injects small amounts of polynucleotide into the superficial skin layers via a fine needle.
The salmon DNA injection procedure takes around 10 to 15 minutes.
You can expect to see improvement in your skin health in four treatment sessions. Since different people have different skin types and responses to salmon DNA treatment, the number of required sessions will vary.
Below is only an estimated timeframe of effects possible with the salmon DNA injection:
3 to 5 Days After First Session
- Softer skin texture
- Reduced sebum (oil) production due to a better balance between oil and moisture of the skin
2 to 4 Weeks After Second Session
- Improved skin elasticity due to self-regeneration of collagen
- Reduced fine wrinkles around the eyes
- Reduced pores and dead cells
4 to 6 Weeks After Third Session
- Skin feels naturally lifted thanks to improvement in skin elasticity
- Skin volume filled out from the dermis layer of the skin
6 to 8 Weeks After Fourth Session
- Rejuvenated skin for a youthful look
Post-treatment, you may see lines of small raised bumps (looking like rows of small mosquito bites) at the site of each injection. The bumps commonly resolve in about 24 hours to completely disperse and 48 hours for the eye area. It is precisely such bumps that tell the artistry of an experienced aesthetic doctor, as this intradermal treatment is injected just under the skin and needs to be injected evenly with a pair of steady hands. There might also be needle marks that one can cover with a little makeup.
It is recommended to take the first four salmon DNA injections, with the first three taken at monthly intervals for the best results. Subsequently, the fourth one can be taken in the sixth month. The number of treatments can vary based on the patient’s skin condition, with some needing four monthly sessions.
You may aim for more hydrated and supple skin that bounces when you can pair this treatment with hyaluronic acid fillers. If you have acne-prone skin, you may consider medical facials as well.
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Frequently Asked Questions About Salmon DNA Injection
One week before the salmon DNA treatment, you should:
- Avoid alcohol consumption
- Stop using skincare products containing glycolic acid
- Protect the treatment area from UV exposure by applying sunscreen daily
- Avoid using make-up on treatment day
Following the application of adequate anaesthetic cream, the procedure typically results in minimal to moderate discomfort. In addition, the salmon DNA injection, with the introduction of polynucleotide beneath the skin, the salmon DNA injection may lead to a mild stinging sensation.
You should be provided with specific post-treatment care instructions, which may include a temporary makeup restriction, after the salmon DNA treatment. It’s generally recommended to avoid wearing makeup immediately after to allow your skin to recover and minimise the risk of infection. Typically, makeup can be applied after a day or as advised by your doctor.
Doctors recommend at least four treatment sessions of the salmon DNA injections. Typically, you may start to see noticeable improvements after these sessions, with cumulative benefits over time. You may also receive a personalised treatment plan based on your skin’s condition and your desired outcome.
Yes, the salmon DNA injection can be combined with other medical aesthetic treatments. You may pair it with hyaluronic dermal fillers to hydrate the skin and give it a more radiant glow. However, if you have specific skincare goals in mind, you can talk to your doctor about them so that they can recommend suitable treatment to complement your salmon DNA treatment.
You may learn more about hydration fillers and other skin boosters here